Why Up the Nose?

About 96% of people taking oral medications said they were dissatisfied with at least one aspect of their medication.*
*In a survey of 3930 US patients using oral acute prescription medication for migraine attacks.
3 key limitations of some pills and dissolvable tablets
They take too long
- To work quickly, oral medications like pills and tablets rely on a digestive system that’s readily able to absorb medication. And often, nausea, vomiting, and other GI-related disorders and symptoms can accompany a migraine attack and delay absorption.
Trudhesa™ delivers medication to the upper nasal space where it can be quickly absorbed and quickly go to work.
3 key limitations of some pills and dissolvable tablets

Actor Portrayal
They don’t last long enough
- In a survey of people who take an oral acute prescription medication, nearly 2 out of 5 reported relief wore off just 24 hours after taking their medication. More than half said they continue to have moderate to severe disability.*
For many, Trudhesa can provide relief that lasts up to 2 days with a single dose, time after time.

They have time limits on dosing
Many oral medications need to be taken within the first 60 minutes of a migraine attack to be most effective. But you know that’s not always possible.
Trudhesa is proven to work on migraine symptoms even when taken late into a migraine attack, so you can take it on your terms.†
Trudhesa may be right for you if:
You need relief that’s Speedy for rapid-onset migraine attacks
- You have sudden, unpredictable migraine attacks that outlast your oral medication
- Your migraine attacks are often accompanied by nausea, vomiting, or other GI issues
You need Steady, long-lasting relief
- Your migraine pain returns within 24 hours of taking
your oral medication - Inconsistent relief makes you worry about your
migraine attack roaring back
You need reliable, at-the-ready relief, even when taken late into a migraine attack
- Sometimes you can’t take your medication within an hour of when a migraine attack starts
- Your go-to migraine medication works sometimes but not others


Goes where migraine pills don’t. Does what migraine pills can’t.
Only Trudhesa uses POD® technology to deliver proven medication to the upper nasal space.
If you’re not getting the relief you need, and you want a medication that can work:
Quickly, and for a long time
Without having to be taken orally
Even when taken late into an attack
When attacks just won’t go away
Ask about Trudhesa.

Give it a Try!
84% of people either agreed or strongly agreed Trudhesa was easy to use‡
*In a survey of 3930 people using oral acute prescription medication for migraine attacks.
†Exploratory efficacy outcomes are based on patient reports and post hoc analyses from a phase 3, open-label safety study of Trudhesa.
‡Results were from a poststudy questionnaire, which asked 354 people to rate their experience with Trudhesa compared to their best usual care at baseline. The results were patient-reported and not validated.

